Youre reading a free article with opinions that may differ from The Motley Fools Premium Investing Services. In the business of drug development, deals can be just as important as scientific breakthroughs. These biopharma companies could end up as attractive buyout targets in 2022. Dealmaking is essential to the business of drug development. . AcelRx (ACRX). This therapeutic has been licensed to Swiss pharma giant Novartis. ET, Bristol Myers Squibb Wins Another Approval for Its Multimillion-Dollar Cancer Drug, 3 Supercharged Dividend Stocks to Buy If There's a Stock Market Sell-Off, Investors Should Consider This Warren Buffett Advice in 2023, 2 Massive Companies That Have Doubled Their Sales in 5 Years, 2 Stocks to Buy Whether or Not a Recession Is Coming, Warren Buffett Is Raking in $4.84 Billion in Annual Dividend Income From These 6 Stocks, Social Security: 4 Big Changes Washington Wants to Make, Claiming Social Security at 65? Best Stocks & ETFs. Always do your own due diligence before buying and selling any stock, and/or consult with a licensed financial adviser. The company has a team of world-class researchers, trying to transform the company-owned CRISPR/Cas9 gene-editing platform into breakthrough human therapeutics. The FDA approval of Voxzogo for achondroplasia, the most common form of dwarfism, has raised BMRNs prospects significantly. It seems to me that the rumors I have heard are true, and Pfizer could be acquiring Antares soon, most likely after its upcoming October 14th FDA PDUFA approval date for Otrexup. Aesther Healthcare Acquisition Corp and Ocean Biomedical, Inc. announced that AEHA has filed with the U.S. Securities and Exchange Commission a definitive proxy statement in connection with its proposed business combination with Ocean and with respect to the special meeting of Aesthers stockholders scheduled to be held on February 3, 2023. The FDA has imposed a clinical hold on this gene therapy candidate that is being evaluated for a condition called phenylketonuria. 5 min read Mergers & acquisitions (M&A) are back in focus in the biotech sector after a tepid run in the last couple of years. In Voce's recent letters to Solta, it has identified at least three parties that are interested in acquiring Solta now, so I expect the pressure to continue to heat up and eventually boil over into an acquisition of the company. An early-stage asset, codenamed BMN 307, is mired in trouble. In the wake of generic drugs eating into the sales of off-patent branded drugs, growing pressure from regulators to reduce the prices of drugs, drying pipelines, and ever-increasing R&D costs, there has been an increasing consolidation within the drug industry. Meanwhile, earlier this month, U.K.-based Elliott Advisors, one of the largest stakeholders in Alexion, urged the company to take a proactive approach and put itself up for sale to maximize the chance of an optimal outcome. The database, which shows drugmaker acquisitions that happened since 2018 and were valued at $50 million or more in upfront consideration, will be regularly updated. But I think there's also a good fit on Seagen's pipeline too. We believe there is merit to the current rumors surrounding AcelRx. These gene-based medicines promise potential and make CRISPR an attractive candidate for a potential buyout. Here's the Stock to Buy Now, Join Nearly 1 Million Premium Members And Get More In-Depth Stock Guidance and Research, Motley Fool Issues Rare All In Buy Alert, Copyright, Trademark and Patent Information. We have been hearing some strong acquisition rumors concerning AcelRx, much like we heard about Obagi last year. Keith Speights owns Bristol Myers Squibb and Vertex Pharmaceuticals. Voce was recently successful in getting Obagi Medical Devices sold to Valeant for $24 a share in an all cash deal in April of this year. There's some people who say that they're disappointed because a company got taken out because they'd rather own the company and profit from the growth of that company individually. Calyxt, Inc. (Nasdaq: CLXT), a plant-based synthetic biology company, and Cibus, a leader in precision gene editing in agriculture, today announced that both companies have entered into a definitive merger agreement under which Calyxt and Cibus will merge in an all-stock transaction. Cellectis announced today that Cibus Global LLC and Calyxt, Inc. (NASDAQ: CLXT) (Calyxt), announced that Calyxt and Calypso Merger Subsidiary, LLC, a Delaware limited liability company and wholly-owned subsidiary of Calyxt, entered into an Agreement and Plan of Merger with Cibus and certain other parties named therein (the Merger Agreement), pursuant to which, subject to the terms and conditions thereof, Calyxt and Cibus will merge in an all-stock transaction. Keep track of M&A as it happens with this database. Let's take a look at some of the biotech companies that have been in the acquisition crosshairs for quite some time. Alnylam stock has a market capitalization of over $20 billion. Biotech M&A - 2021 Deals Search for: Biotech M&A - 2021 Deals. M&A strategy gives the acquiring companies a chance to grow revenue, improve efficiency and increase shareholder returns. Please. Gene-editing company Crispr (NASDAQ:CRSP) has long been considered as a potential M&A target owing to its promising technology platform and its longstanding partnership with Vertex Pharma (NASDAQ:VRTX). Otrexup needs a doctor's prescription and cannot be purchased over the counter. Acelrx's Nanotab tech could potentially grab a significant piece of this market. Enclose phrases in quotes. Immuno-oncology biotech Iovance Biotherapeutics' shares rocketed up by nearly 40% Tuesday on buyout chatter. The Motley Fool has a disclosure policy. Sold Kos Pharmaceuticals to Abbott Laboratories: Mr. King served as Executive Vice President of Commercial Operations of Kos Pharmaceuticals, Inc. See above section for details on that buyout. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Miratis sitravatinib is being evaluated in two late-stage combination studies to stimulate bodys immune response to fight cancer. Gilead Sciences (GILD -1.00%) also has not been shy about making smaller deals. Pharma giant Pfizer recently announced that it will acquire Arena. The FDA has accepted the new drug application for adagrasib in NSCLC, with a PDUFA goal date of Dec. 14, 2022. Sold ATS Medical, Inc. to Medronics Inc. (MDT): Mr. Nohra served on the Board of Directors of ATS Medical, Inc. Medronics bought out ATS Medical for $370M. Even with a market cap of over $2B, we feel Acadia could fetch as much as $6B if the FDA approves pimavanserin, which could happen in the next 6 to 8 months. Sold Pharsight Corporation to Tripos International: Mr. Rosen served on the Board of Directors of Pharsight Corporation. There weren't that many biotech acquisitions in 2021, at least, not compared to other previous years. This year has seen a modest rebound after a slow start, and analysts believe a further resurgence is likely. Beginning on February 10, 2012, Voce Capital sent a letter to the Obagi Board of Directors criticizing the Board's adoption of a poison pill and demanding immediate action to address the company's corporate governance failures. INCY has gained 43% year-to-date and trades around $91. This would be a similar strategy Voce followed with Obagi. In 2013, there were reports that Roche was eyeing BioMarin for a possible acquisition. Today, you can download 7 Best Stocks for the Next 30 Days. 11. As well Dan has 5 years trading futures, specializing in E-minis and Treasury products. Additionally, the database is limited to deals valued at a minimum of $50 million upfront. ATRS. Rumors again surfaced in 2016 that Roche would acquire BioMarin in a deal that could be in the range of $130 to $150 per share. Seagen has quite a few oncology drugs that would work well with the Bristol-Myers drugs. Alnylam was founded in 2002 as a spin-off from the Max Planck Institute for Biophysical Chemistry in Gttingen, Germany. Shockwave Medical, Inc. (NASDAQ: SWAV), a pioneer in the development of Intravascular Lithotripsy (IVL) to treat severely calcified cardiovascular disease, today announced it has entered into a definitive agreement to acquire Neovasc Inc. (NASDAQ,TSX:NVCN), a company focused on the minimally invasive treatment of refractory angina. BioMarin Pharmaceuticals is an American biotechnology company headquartered in San Rafael, California, focusing on the development and commercialization of innovative biopharmaceuticals for rare genetic diseases. *Premiums are calculated from the closing price of the acquired company's shares on the previous trading day. There's a company called Adicet Bio (ACET 0.46%), ticker there is ACET, I believe. Using these acquired allowed for him to completely divest his own and family's money near the top of the market before the 2008 financial crisis. The acquisition will give Merck access to Accelereons promising pipeline candidate sotatercept which is being evaluated for the treatment of pulmonary arterial hypertension (PAH), a progressive and life-threatening blood vessel disorder. The surge in transactions in the pharmaceutical industry saw 16 deals during 2022 - seemingly the largest number in a decade, worth several billion dollars in value. Best Penny Stocks . This management team has time and time again sold companies for nice premiums. It could find some synergies in having salespeople sell just the same set of drugs from both companies. Financial Market Data powered by FinancialContent Services, Inc. All rights reserved. 2023 InvestorPlace Media, LLC. Its lead product candidate, pimavanserin, designed to treat Parkinson's Disease Psychosis (PDP) has completed a. e have heard similar buzz over the last few months, and as mentioned, the buzz makes sense to us, in no small part because Acadia has had quite an epic stock run over the last year. Other approved drugs in the companys portfolio continue to do well. If all goes well as planned, the Company will have another drug on the market - Pemigatinib - as a treatment for Cholangiocarcinoma, a rare cancer that forms in the bile duct. The rumors on Obagi turned out to be correct, as the company was sold last year to Valeant (VRX) for $24 a share. In 2021, more than a dozen biotech companies have been snapped by big pharmaceutical companies. The number of done deals dropped to 92 from 101 in 2020 and 111 in 2019. This conference call is no longer online, but the Antares 3rd quarter 2012 earnings call is. The results of one of biotech's most polarizing clinical trials, an Alnylam Pharmaceuticals study in a rare disease known as transthyretin amyloidosis cardiomyopathy, are expected imminently. Alexion Pharma is no stranger to takeover rumors. Shockwave Medical bolsters medical device portfolio with acquisition of Neovasc. All rights reserved. I also agree with you that Vertex, if there's going to be one of those massive big pharma mergers like we've seen over the last 20 years, some of those massive deals, I think Vertex would be an excellent candidate to be acquired by a bigger company. The speculation gained further ground when Denmark-based Novo Nordisk (NYSE:NVO) announced a deal to buy Dicerna, also a RNAi therapeutic company. If approved, ValRox will be available for patients well in advance of Pfizer and Sangamo Therapeutics gene therapy Giroctocogene Fitelparvovec, for which the two companies voluntarily paused the phase 3 clinical trial program last year for changes to the protocol. Leading gene-editing biotechs CRISPR Therapeutics and Intellia are likely to be acquired at some point. Perhaps Axsome Therapeutics (AXSM 1.32%) -- ticker there's AXSM -- might be a good fit for Biogen. Price as of January 17, 2023, 4:00 p.m. There were a few, but not as many. Founded in the late 1990s by Andrew Mariathasan in New York, with the goal of covering Wall Street for a new generation of investors, RTTNews has expanded steadily over the years to become a trusted provider of content for a wide array of subjects across several platforms. Sold Conceptus to Bayer: Mr. Chung served as the Chief Commercial Officer at Conceptus. He has 7 years of experience investing and trading biotechnology focused equities with a specialty in identifying under-appreciated value in small caps. Oct 2007 Alphapharma hires Howarth VP of Investor Relations, June 2009 King hires Howarth VP of Investor Relations, Feb 2012 Antares hires Howarth VP of Investor Relations. Sold Somatogen to Baxter International (BAX): Dr. Hoffman was the scientific founder of Somatogen Inc. Baxter bought out Somatogen for $189M. Become a Motley Fool member today to get instant access to our top analyst recommendations, in-depth research, investing resources, and more. Many of today's most influential medicines, from the life-saving cancer treatment Keytruda to the anti-inflammatory agent Humira, might not have become so without mergers and acquisitions. (2016). In December 2019, Intra-Cellulars first drug named CAPLYTA was approved by the FDA for the treatment of adult patients with schizophrenia. Sold GenPharm International, Inc. to Medarex, which was then acquired by Bristol-Myers Squibb (BMY): Mr. Rosen served as Director of Corporate Development at GenPharm International. *Average returns of all recommendations since inception. Copyright 2023 InvestorPlace Media, LLC. Total consideration can reflect both cash and equity offered upfront in exchange for the acquired companys shares, but deals in which the upfront payment was not specified, or was less than $50 million, were not included. We first began to hear acquisition rumors in Antares in late 2011. Written by To be acquired at some point CRISPR Therapeutics and Intellia are likely to be at... And trades around $ 91 otrexup needs a doctor 's prescription and can be... Database is limited to deals valued at a minimum of $ 50 million upfront by the FDA of... Stocks for the Next 30 Days investing resources, and more this management has! 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